Heme Attachment Motif Mobility Tunes Cytochrome c Redox Potential. Lea V. Michel, Tao Ye, Sarah E. J. Bowman, Benjamin D. Levin, Megan A. Hahn, Brandy S. Russell, Sean J. Elliott, and Kara L. Bren, Biochemistry 2007, 46, 11753-11760. DOI: 10.1021/bi701177j .
Effects of Heme Pocket Structure and Mobility on Cytochrome c Stability. Xin Wen, Kirti M. Patel, Brandy S. Russell, and Kara L. Bren, Biochemistry 2007, 46,2537-2544. DOI: 10.1021/bi602380v
Cytochrome c552 Mutants: Structure and Dynamics at the Active Site Probed by Multidimensional NMR and Vibration Echo Spectroscopy. Aaron M. Massari, Brian L. McClain, Ilya J. Finkelstein, Andrew P. Lee, Heather L. Reynolds, Kara L. Bren, and Michael D. Fayer, J. Phys. Chem. B 2006, 110, 18803-18810. DOI: 10.1021/jp054959q
Redox Properties of Wild-Type and Heme-Binding Loop Mutants of Bacterial Cytochromes c Measured by Direct Electrochemistry. Tao Ye, Ravinder Kaur, Xin Wen, Kara L. Bren, and Sean J. Elliott, Inorg. Chem., 2005, 44, 8999-9006. DOI: 10.1021/ic051003l
Heme Axial Methionine Fluxion in Pseudomonas aeruginosa Asn64Gln Cytochrome c551. Xin Wen and Kara L. Bren, Inorg. Chem. 2005, 44, 8587-8593. DOI: 10.1021/ic050976i
The Influence of Aqueous versus Glassy Solvents on Protein Dynamics: Vibrational Echo Experiments and Molecular Dynamics Simulations. Aaron M. Massari, Ilya J. Finkelstein, Brian L. McClain, Anne Goj, Xin Wen, Kara L. Bren, Roger F. Loring, and Michael D. Fayer, J. Am. Chem. Soc. 2005, 127, 14279-14289. DOI: 10.1021/ja053627w
An Obligatory Intermediate in the Folding Pathway of Cytochrome c552 from Hydrogenobacter thermophilus. Carlo Travaglini-Allocatelli, Stefano Gianni, Vikash K. Dubey, Allesandro Borgia, Adele Di Matteo, Daniele Bonivento, Francesca Cutruzzolà, Kara L. Bren, and Maurizio Brunori, J. Biol. Chem. 2005, 280, 25729-25734. DOI: 10.1074/jbc.M502628200
Suppression of Axial Methionine Fluxion in Hydrogenobacter thermophilus Gln64Asn-Cytochrome c552. Xin Wen and Kara L. Bren, Biochemistry 2005, 44, 5225-5233. DOI: 10.1021/bi047556+.
Folding, Conformational Changes, and Dynamics of Cytochromes c Probed by NMR Spectroscopy. Kara L. Bren, Jason A. Kellogg, Ravinder Kaur, and Xin Wen, Inorg. Chem. 2004, 43, 7934-7944. DOI: 10.1021/ic048925t
Cytochrome rC552, Formed During Expression of the Truncated, Thermus thermophilus Cytochrome c552 Gene in the Cytoplasm of Escherichia coli, Reacts Spontaneously to Form Protein-Bound, 2-Formyl-4-vinyl (Spirographis) Heme. James A. Fee, Thomas R. Todaro, Eugene Luna, Donita Sanders, Laura Hunsicker-Wang, Kirti M. Patel, Kara L. Bren, Ester Gomez-Moran, Michael G. Hill, Jingyuan Ai, Thomas M. Loehr, W. Anthony Oertling, Pamela A. Williams, C. David Stout, Duncan McRee, and Andrzej Pastuszyn, Biochemistry 2004, 43, 12162-12176. DOI: 10.1021/bi048968l
Heme Axial Methionine Fluxionality in Hydrogenobacter thermophilus Cytochrome c552. Linghao Zhong, Xin Wen, Terry M. Rabinowitz, Brandy S. Russell, Elizabeth F. Karan, Kara L. Bren, Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 8637-8642. DOI: 10.1073/pnas.0402033101
Backbone Dynamics and Hydrogen Exchange of Oxidized Pseudomonas aeruginosa Ferricytochrome c551. Brandy S. Russell, Linghao Zhong, Maria Giulia Bigotti, Francesca Cutruzzolà, and Kara L. Bren, J. Biol. Inorg. Chem. 2003, 8, 156-166. DOI: 10.1007/s00775-002-0401-z
Characterization of Recombinant Horse Cytochrome c Synthesized with the Assistance of Escherichia coli Cytochrome c Maturation Factors. Jason A. Kellogg and Kara L. Bren, Biochim. Biophys. Acta 2002, 1601, 215-221. DOI: 10.1016/S1570-9639(02)00471-5
Denaturant Dependence of Equilibrium Unfolding Intermediates and Denatured State Structure of Horse Ferricytochrome c. Brandy S. Russell and Kara L. Bren, J. Biol. Inorg. Chem. 2002, 7, 909-916. DOI: 10.1007/s00775-002-0381-z
Peptide Mimotopes of Pneumococcal Capsular PS of 6B Serotype. A Peptide Mimotope Can Bind to Two Unrelated Antibodies. Jeon-Soo Shin, Jigui Yu, Jisheng Lin, Linghao Zhong, Kara L. Bren, and Moon H. Nahm., J. Immunol. 2002, 168, 6273-6278. http://www.jimmunol.org/cgi/reprint/168/12/6273
Characterization of Hydrogenobacter thermophilus Cytochromes c552 Expressed in the Cytoplasm and Periplasm of Escherichia coli. Elizabeth F. Karan, Brandy S. Russell and Kara L. Bren, J. Biol. Inorg. Chem. 2002, 7, 260-272. DOI: 10.1007/s007750100292
Recombinant Cytochrome rC557 Obtained from Escherichia coli Cells Expressing a Truncated Thermus thermophilus cycA gene: Heme Inversion in an Improperly Matured Protein. Duncan E. McRee, Pamela A. Williams, Vandana Sridhar, Andrzej Pastuszyn, Kara L. Bren, Kirti M. Patel, Ying Chen, Thomas R. Todaro, Donita Sanders, Eugene Luna, and James A. Fee, J. Biol. Chem. 2001, 276, 6537-6544. DOI: 10.1074/jbc.M008421200
Integrity of Thermus thermophilus Cytochrome c552 Synthesized by Escherichia coli Cells Expressing the Host-Specific Cytochrome c Maturation Genes, ccmABCDEFGH: Biochemical, Spectral and Structural Characterization of the Recombinant Protein. James A. Fee, Ying Chen, Thomas R. Todaro, Kara L. Bren, Kirti M. Patel, Michael G. Hill, Ester Gomez-Moran, Thomas M. Loehr, Jingyuan Ai, Linda Thöny-Meyer, Pamela A. Williams, Enrico Stura, Vandana Sridhar, and Duncan E. McRee, Protein Sci. 2000, 9, 2074-2084
NMR Investigation of Ferricytochrome c Unfolding: Detection of an Equilibrium Unfolding Intermediate and Residual Structure in the Denatured State. Brandy S. Russell, Rory Melenkivitz, and Kara L. Bren, Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 8312-8317. DOI: 10.1073/pnas.150239397